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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Digital Diagnostics</journal-id><journal-title-group><journal-title xml:lang="en">Digital Diagnostics</journal-title><trans-title-group xml:lang="ru"><trans-title>Digital Diagnostics</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Digital Diagnostics</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2712-8490</issn><issn publication-format="electronic">2712-8962</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">110952</article-id><article-id pub-id-type="doi">10.17816/DD110952</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи и серии клинических случаев</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>临床病例及临床病例的系列</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Latent course of Crohn’s disease: the role of tomographic imaging in diagnosis</article-title><trans-title-group xml:lang="ru"><trans-title>Скрытое течение болезни Крона: роль томографических методов в диагностике</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>克罗恩病的潜伏过程：断层扫描方法在诊断中的作用</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8521-4045</contrib-id><name-alternatives><name xml:lang="en"><surname>Shumskaya</surname><given-names>Yuliya F.</given-names></name><name xml:lang="ru"><surname>Шумская</surname><given-names>Юлия Федоровна</given-names></name><name xml:lang="zh"><surname>Shumskaya</surname><given-names>Yuliya F.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>yu.shumskaia@npcmr.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6718-8701</contrib-id><contrib-id contrib-id-type="spin">3097-4977</contrib-id><name-alternatives><name xml:lang="en"><surname>Nefedova</surname><given-names>Tamara S.</given-names></name><name xml:lang="ru"><surname>Нефедова</surname><given-names>Тамара Сергеевна</given-names></name><name xml:lang="zh"><surname>Nefedova</surname><given-names>Tamara S.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>prosto.toma.22@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7705-9754</contrib-id><contrib-id contrib-id-type="spin">6983-5991</contrib-id><name-alternatives><name xml:lang="en"><surname>Akhmedzyanova</surname><given-names>Dina A.</given-names></name><name xml:lang="ru"><surname>Ахмедзянова</surname><given-names>Дина Альфредовна</given-names></name><name xml:lang="zh"><surname>Akhmedzyanova</surname><given-names>Dina A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>dina_akhm@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2681-9378</contrib-id><contrib-id contrib-id-type="spin">3306-1387</contrib-id><name-alternatives><name xml:lang="en"><surname>Blokhin</surname><given-names>Ivan A.</given-names></name><name xml:lang="ru"><surname>Блохин</surname><given-names>Иван Андреевич</given-names></name><name xml:lang="zh"><surname>Blokhin</surname><given-names>Ivan A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>i.blokhin@npcmr.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9337-7453</contrib-id><contrib-id contrib-id-type="spin">2015-1822</contrib-id><name-alternatives><name xml:lang="en"><surname>Mnatsakanyan</surname><given-names>Marina G.</given-names></name><name xml:lang="ru"><surname>Мнацаканян</surname><given-names>Марина Генриковна</given-names></name><name xml:lang="zh"><surname>Mnatsakanyan</surname><given-names>Marina G.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>д.м.н.</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Med.)</p></bio><email>mnatsakanyan08@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">The First Sechenov Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution></aff><aff><institution xml:lang="zh">The First Sechenov Moscow State Medical University (Sechenov University)</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies</institution></aff><aff><institution xml:lang="ru">Научно-практический клинический центр диагностики и телемедицинских технологий</institution></aff><aff><institution xml:lang="zh">Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2022-11-21" publication-format="electronic"><day>21</day><month>11</month><year>2022</year></pub-date><pub-date date-type="pub" iso-8601-date="2022-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2022</year></pub-date><volume>3</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>394</fpage><lpage>402</lpage><history><date date-type="received" iso-8601-date="2022-09-16"><day>16</day><month>09</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-10-11"><day>11</day><month>10</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Эко-вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2022, Eco-Vector</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-вектор</copyright-holder><copyright-holder xml:lang="zh">Eco-Vector</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://jdigitaldiagnostics.com/DD/article/view/110952">https://jdigitaldiagnostics.com/DD/article/view/110952</self-uri><abstract xml:lang="en"><p>Crohn’s disease with localization in the upper gastrointestinal tract, terminal ileum, or colon is diagnosed based on visualization of the lesion area using endoscopic methods and histological examination. In cases of damage to the small intestine, when endoscopy methods are not informative enough and the use of videocapsular endoscopy has a number of contraindications, it is advised to use radiation diagnostic methods, such as multispiral computed tomography and/or magnetic resonance enterography, to make a diagnosis.</p> <p>We present a clinical case of ambiguous clinical manifestations of Crohn’s disease with small intestine and rectal involvement. Tomographic imaging was used to confirm the diagnosis. A 44-year-old patient presented with complaints of non-pronounced abdominal pain, dyspepsia. The lab panel showed indirect signs of malabsorption, an increase in fecal calprotectin. An endoscopic examination with histological verification revealed a picture of proctitis. After performing computed tomography and/or magnetic resonance enterography multiple lesions of the small intestine were revealed. This clinical case demonstrates an atypical clinical picture of Crohn’s disease with jejunal, iliac, and rectal lesions.</p> <p>The patient had no characteristic complaints; the results of endoscopic and morphological studies were not informative. Imaging by means of computed and magnetic resonance tomography has played a crucial role in the diagnosis and successful treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Болезнь Крона с локализацией процесса в верхних отделах желудочно-кишечного тракта, терминальном отделе подвздошной кишки или в толстой кишке диагностируется на основании визуализации области поражения при помощи эндоскопических методов исследования и гистологического исследования биоптатов. В случаях поражения тонкой кишки, когда методы эндоскопии малоинформативны, а применение видеокапсульной эндоскопии имеет ряд противопоказаний, для постановки диагноза целесообразно использовать лучевые методы диагностики, такие как мультиспиральная компьютерная томография и/или магнитно-резонансная энтерография.</p> <p>Приводим описание клинического случая пациента со стёртыми клиническими проявлениями болезни Крона с поражением тонкой и прямой кишки, диагноз которому удалось верифицировать благодаря применению томографических лучевых методов исследования. Мужчина в возрасте 44 лет с жалобами на невыраженные боли в животе, диспепсию. В анализах ― косвенные признаки мальабсорбции, повышение фекального кальпротектина; при эндоскопическом обследовании с гистологической верификацией ― картина проктита. После выполнения энтерографии с помощью компьютерной и магнитно-резонансной томографии удалось диагностировать массивное поражение тонкой кишки, являющееся субстратом симптоматики.</p> <p>Приведённый клинический случай демонстрирует атипичную клиническую картину болезни Крона с поражением петель тощей, подвздошной и отделов прямой кишки. В отсутствии характерных жалоб у пациента, а также вследствие недостаточно информативных результатов эндоскопического и морфологического исследования такие методы визуализации, как компьютерная и магнитно-резонансная томография, сыграли решающую роль в постановке диагноза.</p></trans-abstract><trans-abstract xml:lang="zh"><p>上消化道、回肠末端或结肠局部的克罗恩病是通过内镜检查和活检标本的组织学检查观察病变而诊断的。在小肠受累的情况下，内镜检查的价值不大，视频胶囊内镜检查有一些禁忌症，建议使用放射学技术，如多螺旋计算机断层扫描和/或磁共振肠成像来进行诊断。</p> <p>这里描述的是一位临床表现轻微的克罗恩病患者，其小肠和直肠受累，通过使用影像放射学技术验证了其诊断。一名44岁的男子，有轻微腹痛和消化不良。检查显示，有吸收不良的间接迹象，粪便钙蛋白增加；内镜检查与组织学验证显示，有直肠炎的模式。经过计算机断层扫描和磁共振成像肠道造影，可以诊断出小肠的巨大病变，这是症状的基底。</p> <p>这个临床病例显示了克罗恩病的非典型临床表现，包括空肠、回肠和直肠受累。由于患者没有特征性的主诉，并且由于内窥镜和形态学检查的结果信息量不足，CT和MRI等影像技术在诊断中起到了决定性的作用。</p></trans-abstract><kwd-group xml:lang="en"><kwd>Crohn’s disease</kwd><kwd>MRI-enterography</kwd><kwd>CT-enterography</kwd><kwd>clinical case</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>болезнь Крона</kwd><kwd>МР-энтерография</kwd><kwd>КТ-энтерография</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>克罗恩病</kwd><kwd>磁共振小肠造影</kwd><kwd>CT小肠造影</kwd><kwd>临床病例</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Ainouche A, Durot C, Soyer P, et al. 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