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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Digital Diagnostics</journal-id><journal-title-group><journal-title xml:lang="en">Digital Diagnostics</journal-title><trans-title-group xml:lang="ru"><trans-title>Digital Diagnostics</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Digital Diagnostics</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2712-8490</issn><issn publication-format="electronic">2712-8962</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">112093</article-id><article-id pub-id-type="doi">10.17816/DD112093</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи и серии клинических случаев</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>临床病例及临床病例的系列</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Diseases and abnormalities of the nipple-areolar complex: a case report series</article-title><trans-title-group xml:lang="ru"><trans-title>Диагностика патологии и аномалии сосково-ареолярного комплекса: серия клинических случаев</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>乳头乳晕复合体的病理和异常的诊断： 一系列临床病例</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6745-1672</contrib-id><name-alternatives><name xml:lang="en"><surname>Karanadze</surname><given-names>Elena N.</given-names></name><name xml:lang="ru"><surname>Каранадзе</surname><given-names>Елена Николаевна</given-names></name><name xml:lang="zh"><surname>Karanadze</surname><given-names>Elena N.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>ekaranadze@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5649-2193</contrib-id><contrib-id contrib-id-type="spin">8449-6590</contrib-id><name-alternatives><name xml:lang="en"><surname>Sinitsyn</surname><given-names>Valentin E.</given-names></name><name xml:lang="ru"><surname>Синицын</surname><given-names>Валентин Евгеньевич</given-names></name><name xml:lang="zh"><surname>Sinitsyn</surname><given-names>Valentin E.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Med), Professor</p></bio><email>info@npcmr.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-1723-6796</contrib-id><name-alternatives><name xml:lang="en"><surname>Karanadze</surname><given-names>Mariia A.</given-names></name><name xml:lang="ru"><surname>Каранадзе</surname><given-names>Мария Алексеевна</given-names></name><name xml:lang="zh"><surname>Karanadze</surname><given-names>Mariia A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>ekaranadze@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Clinical Diagnostic Center MEDSI on Krasnaya Presnya</institution></aff><aff><institution xml:lang="ru">Клинико-диагностический центр МЕДСИ на Красной Пресне</institution></aff><aff><institution xml:lang="zh">Clinical Diagnostic Center MEDSI on Krasnaya Presnya</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Lomonosov Moscow State University, Medical Scientific and Educational Center</institution></aff><aff><institution xml:lang="ru">Московский государственный университет имени М.В. Ломоносова, Медицинский научно-образовательный центр</institution></aff><aff><institution xml:lang="zh">Lomonosov Moscow State University, Medical Scientific and Educational Center</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">The Russian National Research Medical University named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution></aff><aff><institution xml:lang="zh">The Russian National Research Medical University named after N.I. Pirogov</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-04-03" publication-format="electronic"><day>03</day><month>04</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2023-04-19" publication-format="electronic"><day>19</day><month>04</month><year>2023</year></pub-date><volume>4</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>51</fpage><lpage>60</lpage><history><date date-type="received" iso-8601-date="2022-10-26"><day>26</day><month>10</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2023-03-24"><day>24</day><month>03</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-вектор</copyright-holder><copyright-holder xml:lang="zh">Eco-Vector</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://jdigitaldiagnostics.com/DD/article/view/112093">https://jdigitaldiagnostics.com/DD/article/view/112093</self-uri><abstract xml:lang="en"><p>The nipple–areolar complex is a specific anatomical and histological structure. Normal structure and pathological process variabilities and the complexity of diagnostic imaging cause difficulties for radiologists and physicians. Breast magnetic resonance imaging is highly sensitive for structural features and nipple-areolar complex cancer detection. Magnetic resonance imaging is a useful diagnostic tool when mammography and ultrasound findings are inconclusive. It allows visualization of the retroareolar region, suitable for the diagnosis of papillomas, adenomas, Paget’s disease, ductal carcinoma in situ, and invasive ductal carcinoma.</p> <p>This is a case report on identifying the pathology and anomalies of the nipple-areolar complex, which may benefit radiologists, gynecologists, and residents.</p></abstract><trans-abstract xml:lang="ru"><p>Сосково-ареолярный комплекс ― особая анатомическая и гистологическая структура. Вариабельность нормального строения, широкий спектр патологических процессов и сложность диагностической визуализации вызывают трудности у врачей лучевой диагностики и клиницистов.</p> <p>Наиболее часто в диагностике патологии сосково-ареолярного комплекса используют ультразвуковую диагностику и маммографию. При неоднозначных результатах предшествующих методов и для оценки распространённости процесса применяют магнитно-резонансную томографию с внутривенным контрастированием.</p> <p>Магнитно-резонансная томография молочной железы ― наиболее чувствительный метод выявления особенностей строения, диагностики доброкачественных и злокачественных заболеваний, затрагивающих сосково-ареолярный комплекс. Магнитно-резонансная томография полезна в качестве дополнительного диагностического инструмента при неоднозначных результатах маммографии и ультразвукового исследования. Магнитно-резонансная томография позволяет визуализировать ретроареолярную зону, подходит для диагностики папиллом, аденом, болезни Педжета, протоковой карциномы <italic>in situ</italic> и инвазивного рака.</p> <p>В статье дано описание клинических случаев диагностики патологии и аномалий сосково-ареолярного комплекса, что может быть полезно для врачей лучевой диагностики, гинекологов, клинических ординаторов.</p></trans-abstract><trans-abstract xml:lang="zh"><p>乳头乳晕复合体是一种特殊的解剖学和组织学结构。正常结构的变异性、病理过程的广泛性和诊断成像的复杂性给放射科医生和临床医生带来困难。乳房磁共振成像是检测结构特征、诊断涉及乳头乳晕复合体的良性和恶性疾病的最灵敏方法。在乳腺钼靶和超声检查结果不明确的情况下，磁共振成像作为一种额外的诊断工具非常有用。磁共振成像允许看到乳腺后区，适合诊断乳头瘤、腺瘤、佩吉特氏病、导管原位癌和浸润性癌。</p> <p>我们在这篇文章中描述了乳头乳晕复合体的病理和异常的临床病例，这可能会对放射科医生、妇科医生和临床住院医师有用。</p></trans-abstract><kwd-group xml:lang="en"><kwd>case report</kwd><kwd>breast disease</kwd><kwd>nipple-areolar complex</kwd><kwd>mammography</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>клинический случай</kwd><kwd>рак молочной железы</kwd><kwd>сосково-ареолярный комплекс</kwd><kwd>маммография</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>临床病例</kwd><kwd>乳腺癌</kwd><kwd>乳头乳晕复合体</kwd><kwd>乳腺钼靶</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Stone K, Wheeler A. 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