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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Digital Diagnostics</journal-id><journal-title-group><journal-title xml:lang="en">Digital Diagnostics</journal-title><trans-title-group xml:lang="ru"><trans-title>Digital Diagnostics</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Digital Diagnostics</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2712-8490</issn><issn publication-format="electronic">2712-8962</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">430128</article-id><article-id pub-id-type="doi">10.17816/DD430128</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи и серии клинических случаев</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>临床病例及临床病例的系列</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Chronic esophageal fistula as a rare cause of secondary osteomyelitis of the thoracic spine</article-title><trans-title-group xml:lang="ru"><trans-title>Хронический пищеводный свищ как редкая причина вторичного остеомиелита грудного отдела позвоночника</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>慢性食管瘘作为继发性胸椎骨髓炎的罕见病因</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7956-3719</contrib-id><name-alternatives><name xml:lang="en"><surname>Zarya</surname><given-names>Valeriya A.</given-names></name><name xml:lang="ru"><surname>Заря</surname><given-names>Валерия Алексеевна</given-names></name><name xml:lang="zh"><surname>Zarya</surname><given-names>Valeriya A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>zariandra@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3251-4084</contrib-id><contrib-id contrib-id-type="spin">7824-5374</contrib-id><name-alternatives><name xml:lang="en"><surname>Gavrilov</surname><given-names>Pavel V.</given-names></name><name xml:lang="ru"><surname>Гаврилов</surname><given-names>Павел Владимирович</given-names></name><name xml:lang="zh"><surname>Gavrilov</surname><given-names>Pavel V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>spbniifrentgen@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6760-2426</contrib-id><contrib-id contrib-id-type="spin">6342-8967</contrib-id><name-alternatives><name xml:lang="en"><surname>Makogonova</surname><given-names>Marina E.</given-names></name><name xml:lang="ru"><surname>Макогонова</surname><given-names>Марина Евгеньевна</given-names></name><name xml:lang="zh"><surname>Makogonova</surname><given-names>Marina E.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>MakogonovaME@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3192-1430</contrib-id><name-alternatives><name xml:lang="en"><surname>Kozak</surname><given-names>Andrey  R.</given-names></name><name xml:lang="ru"><surname>Козак</surname><given-names>Андрей Романович</given-names></name><name xml:lang="zh"><surname>Kozak</surname><given-names>Andrey  R.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>andrkozak@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9186-6461</contrib-id><contrib-id contrib-id-type="spin">4918-1046</contrib-id><name-alternatives><name xml:lang="en"><surname>Vishnevskiy</surname><given-names>Arkadiy  A.</given-names></name><name xml:lang="ru"><surname>Вишневский</surname><given-names>Аркадий Анатольевич</given-names></name><name xml:lang="zh"><surname>Vishnevskiy</surname><given-names>Arkadiy  A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Med.)</p></bio><email>vichnevsky@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saint-Petersburg State Research Institute of Phthisiopulmonology</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии</institution></aff><aff><institution xml:lang="zh">Saint-Petersburg State Research Institute of Phthisiopulmonology</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-08-30" publication-format="electronic"><day>30</day><month>08</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2023-09-26" publication-format="electronic"><day>26</day><month>09</month><year>2023</year></pub-date><volume>4</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>403</fpage><lpage>410</lpage><history><date date-type="received" iso-8601-date="2023-05-16"><day>16</day><month>05</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-08-22"><day>22</day><month>08</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-вектор</copyright-holder><copyright-holder xml:lang="zh">Eco-Vector</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://jdigitaldiagnostics.com/DD/article/view/430128">https://jdigitaldiagnostics.com/DD/article/view/430128</self-uri><abstract xml:lang="en"><p>Infectious diseases affecting the spine are inflammatory destructive diseases that involved the organ and its structural elements as a result of infection by hematogenic, lymphogenic, or contact pathways, including may be a complication of surgical intervention. In arriving at an accurate diagnosis, it is extremely important to evaluate the anamnesis, the clinical picture, as well as the data of laboratory studies and radiation diagnostics in the aggregate.</p> <p>This article presents a clinical case with the development of secondary ThVII–ThVIII vertebral spondylitis due to esophageal fistula. At the initial diagnosis, spondylitis was associated with spinal anesthesia performed six months prior to onset of the disease, as there was a fistulous defect on the skin in the lumbar region. Consequently, surgical interventions were performed three times in a surgical hospital at the place of residence. The data from the endoscopic examination, as well as the patient’s complaints regarding the relationship between meals, the appearance of pain, and the nature of the discharge from the fistula were not taken into account by doctors initially. With the help of an additional examination, including computed tomography of the esophagus with oral contrast and computed tomography fistulography, the main diagnosis was esophageal fistula. Thoracic spondylitis was only a secondary complication.</p> <p>Thus, the final diagnosis of back pain and fistula in the lumbar region should be formulated after differential diagnosis with alternative diseases of the spine.</p></abstract><trans-abstract xml:lang="ru"><p>Инфекционные заболевания позвоночника представляют собой воспалительные деструктивные заболевания органа и его структурных элементов в результате инфицирования гематогенным, лимфогенным или контактным путём, в том числе могут являться осложнением хирургического вмешательства. При постановке диагноза крайне важно оценивать в совокупности анамнез, клиническую картину, а также данные лабораторных исследований и лучевой диагностики.</p> <p>В работе представлен клинический случай вторично развившегося спондилита позвонков ТhVII–ТhVIII вследствие пищеводного свища. При первичной диагностике спондилит связали со спинальной анестезией, которая проводилась за 6 месяцев до начала заболевания, так как имел место свищевой дефект на коже в поясничной области. По этому поводу трижды проводились оперативные вмешательства в хирургическом стационаре по месту жительства. Данные эндоскопического исследования и жалобы пациентки на связь между приёмами пищи, появлением болей и характером отделяемого из свища не были приняты врачами изначально во внимание. С помощью дополнительного обследования, включающего компьютерную томографию пищевода с пероральным контрастированием и компьютерно-томографическую фистулографию, был установлен основной диагноз «Свищ пищевода», а спондилит грудного отдела позвоночника оказался лишь вторичным осложнением.</p> <p>Таким образом, окончательный диагноз при болях в спине, обусловленных не только инфицированием, но и являющихся осложнением хирургического вмешательства, должен формулироваться после проведения дифференциальной диагностики с альтернативными заболеваниями позвоночника.</p></trans-abstract><trans-abstract xml:lang="zh"><p>脊柱感染性疾病是由于血源性、淋巴原性或接触性感染（包括手术并发症）引起的器官及其结构元素的炎症性破坏性疾病。在进行诊断时，对病史、临床表现以及实验室检查和放射诊断数据进行评估极为重要。</p> <p>本文介绍一例因食管瘘引起的ThVII-ThVIII椎骨继发性脊椎炎的临床病例。在最初诊断时，医生认为脊椎炎与脊髓麻醉有关，而脊髓麻醉是在发病前6个月进行的，因为腰部皮肤上有瘘管缺损。这次在居住地的外科医院进行了三次手术治疗。医生最初并没有考虑到内窥镜检查结果以及病人关于进食、疼痛和瘘管分泌物性质之间关系的主诉。在额外检查的帮助下，包括口服造影剂的食道CT扫描和瘘管CT造影，确定了食管瘘的主要诊断，而胸椎脊椎炎只是次要并发症。</p> <p>因此，在存在背痛的原因不仅是感染，还可能是手术治疗的并发症的情况下，最终诊断应该是在与其他脊柱疾病进行鉴别诊断后再做出的。</p></trans-abstract><kwd-group xml:lang="en"><kwd>osteomyelitis</kwd><kwd>spondylitis</kwd><kwd>esophageal fistula</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>остеомиелит</kwd><kwd>спондилит</kwd><kwd>свищ пищевода</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>骨髓炎</kwd><kwd>脊椎炎</kwd><kwd>食管瘘</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Mushkin AYu, Vishnevsky AA. 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