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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Digital Diagnostics</journal-id><journal-title-group><journal-title xml:lang="en">Digital Diagnostics</journal-title><trans-title-group xml:lang="ru"><trans-title>Digital Diagnostics</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Digital Diagnostics</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2712-8490</issn><issn publication-format="electronic">2712-8962</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">568134</article-id><article-id pub-id-type="doi">10.17816/DD568134</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи и серии клинических случаев</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>临床病例及临床病例的系列</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Difficulty in the differential diagnosis of peritoneal carcinomatosis and tuberculosis in a young female patient with ascites: a case report</article-title><trans-title-group xml:lang="ru"><trans-title>Сложность дифференциальной диагностики карциноматоза и туберкулёза брюшины у молодой пациентки с асцитом: описание случая</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>一名年轻腹水患者腹膜转移癌和腹部结核的鉴别诊断难题：病例介绍</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6718-8701</contrib-id><contrib-id contrib-id-type="spin">3097-4977</contrib-id><name-alternatives><name xml:lang="en"><surname>Nefedova</surname><given-names>Tamara S.</given-names></name><name xml:lang="ru"><surname>Нефедова</surname><given-names>Тамара Сергеевна</given-names></name><name xml:lang="zh"><surname>Nefedova</surname><given-names>Tamara S.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>prosto.toma.22@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8521-4045</contrib-id><contrib-id contrib-id-type="spin">3164-5518</contrib-id><name-alternatives><name xml:lang="en"><surname>Shumskaya</surname><given-names>Yuliya F.</given-names></name><name xml:lang="ru"><surname>Шумская</surname><given-names>Юлия Федоровна</given-names></name><name xml:lang="zh"><surname>Shumskaya</surname><given-names>Yuliya F.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>yu.shumskaia@npcmr.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6759-6820</contrib-id><contrib-id contrib-id-type="spin">4872-7130</contrib-id><name-alternatives><name xml:lang="en"><surname>Yurazh</surname><given-names>Marta V.</given-names></name><name xml:lang="ru"><surname>Юраж</surname><given-names>Марта Валерьевна</given-names></name><name xml:lang="zh"><surname>Yurazh</surname><given-names>Marta V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>yurazh_m_v@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4324-7615</contrib-id><contrib-id contrib-id-type="spin">5747-9842</contrib-id><name-alternatives><name xml:lang="en"><surname>Panferov</surname><given-names>Alexandr S.</given-names></name><name xml:lang="ru"><surname>Панферов</surname><given-names>Александр Сергеевич</given-names></name><name xml:lang="zh"><surname>Panferov</surname><given-names>Alexandr S.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.), Assistant Professor</p></bio><email>panferov_a_s@staff.sechenov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0496-4504</contrib-id><contrib-id contrib-id-type="spin">8293-6144</contrib-id><name-alternatives><name xml:lang="en"><surname>Senchikhin</surname><given-names>Pavel V.</given-names></name><name xml:lang="ru"><surname>Сенчихин</surname><given-names>Павел Владимирович</given-names></name><name xml:lang="zh"><surname>Senchikhin</surname><given-names>Pavel V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>paulus200271@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-4885-3321</contrib-id><contrib-id contrib-id-type="spin">5923-8630</contrib-id><name-alternatives><name xml:lang="en"><surname>Grabarnik</surname><given-names>Alexei E.</given-names></name><name xml:lang="ru"><surname>Грабарник</surname><given-names>Алексей Ефимович</given-names></name><name xml:lang="zh"><surname>Grabarnik</surname><given-names>Alexei E.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>a.grabarnik@mail.ru</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2167-8908</contrib-id><contrib-id contrib-id-type="spin">6885-6834</contrib-id><name-alternatives><name xml:lang="en"><surname>Shchekoturov</surname><given-names>Igor O.</given-names></name><name xml:lang="ru"><surname>Щекотуров</surname><given-names>Игорь Олегович</given-names></name><name xml:lang="zh"><surname>Shchekoturov</surname><given-names>Igor O.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>samaramail@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9337-7453</contrib-id><contrib-id contrib-id-type="spin">2015-1822</contrib-id><name-alternatives><name xml:lang="en"><surname>Mnatsakanyan</surname><given-names>Marina G.</given-names></name><name xml:lang="ru"><surname>Мнацаканян</surname><given-names>Марина Генриковна</given-names></name><name xml:lang="zh"><surname>Mnatsakanyan</surname><given-names>Marina G.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Med.), Professor</p></bio><email>mnatsakanyan08@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">The First Sechenov Moscow State Medical University</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова</institution></aff><aff><institution xml:lang="zh">The First Sechenov Moscow State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies</institution></aff><aff><institution xml:lang="ru">Научно-практический клинический центр диагностики и телемедицинских технологий</institution></aff><aff><institution xml:lang="zh">Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">National Medical Research Center for Phthisiopulmonology and Infectious Diseases</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний</institution></aff><aff><institution xml:lang="zh">National Medical Research Center for Phthisiopulmonology and Infectious Diseases</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Moscow Scientific and Clinical Center for Tuberculosis Control</institution></aff><aff><institution xml:lang="ru">Московский городской научно-практический центр борьбы с туберкулёзом</institution></aff><aff><institution xml:lang="zh">Moscow Scientific and Clinical Center for Tuberculosis Control</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-11-16" publication-format="electronic"><day>16</day><month>11</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2023-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2023</year></pub-date><volume>4</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>643</fpage><lpage>652</lpage><history><date date-type="received" iso-8601-date="2023-08-08"><day>08</day><month>08</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-11-07"><day>07</day><month>11</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-вектор</copyright-holder><copyright-holder xml:lang="zh">Eco-Vector</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://jdigitaldiagnostics.com/DD/article/view/568134">https://jdigitaldiagnostics.com/DD/article/view/568134</self-uri><abstract xml:lang="en"><p>The differential diagnosis between peritoneal tuberculosis and peritoneal carcinomatosis is quite challenging because of the similarity of the clinical picture and laboratory and instrumental examination data. Peritoneal tuberculosis and peritoneal carcinomatosis may present with the development of ascites, lymph nodes, and intestinal loop conglomerates. This article presents the clinical case of a young patient who, after her second childbirth, noted the appearance of intense pain in the neck and between the scapulae. Two months later, she experienced pneumonia with a positive reaction to antibiotic therapy. After another 2 months, she experienced recurrent ascites and gastrointestinal symptoms for the first time. The examination revealed ovarian masses and signs of peritoneal carcinomatosis and lung nodules. However, the clinical presentation was atypical for peritoneal carcinomatosis, and lung lesions were suspicious for tuberculosis, which allowed us to hypothesize the presence of tuberculosis of multiple localizations. The diagnosis was confirmed by laparoscopy with a biopsy of the involved tissues and subsequent histological and laboratory confirmation of the etiological role of <italic>Mycobacterium tuberculosis</italic>. The described case demonstrates the importance of using all available diagnostic methods to establish the causes of ascites in young female patients for differential diagnosis between specific and neoplastic etiologies.</p></abstract><trans-abstract xml:lang="ru"><p>Сложность дифференциальной диагностики между туберкулёзом брюшины и карциноматозом брюшины заключается в схожести клинической картины, а также данных лабораторных и инструментальных методов обследования. Туберкулёз брюшины, так же, как и карциноматоз брюшины, может сопровождаться развитием асцита, конгломератов лимфоузлов и петель кишечника.</p> <p>В статье описано клиническое наблюдение молодой пациентки, которая после вторых родов отметила появление интенсивных болей в шее, между лопатками. В дальнейшем, через два месяца с начала симптомов, пациентка перенесла пневмонию с положительным ответом на антибактериальную терапию. Ещё через два месяца она впервые отметила появление рецидивирующего асцита и гастроинтестинальной симптоматики. При обследовании были выявлены изменения яичников и признаки карциноматоза брюшины, а также очаги в лёгких. Однако нетипичная для карциноматоза брюшины клиническая картина и специфическое поражение лёгких позволили заподозрить туберкулёз множественных локализаций. Диагноз был подтверждён по данным лапароскопии с биопсией поражённых тканей и последующим гистологическим и лабораторным подтверждением этиологической роли <italic>Mycobacterium tuberculosis.</italic></p> <p>Описанный случай показывает важность использования всех доступных методов диагностики в установлении причин асцита у молодых пациенток для дифференциальной диагностики между специфической и неопластической этиологией.</p></trans-abstract><trans-abstract xml:lang="zh"><p>腹部结核和腹膜转移癌的鉴别诊断难点在于临床表现、实验室和仪器检查方法的数据的相似性。腹腔结核和腹膜转移癌都可能伴有腹水、淋巴聚集体和肠襻的形成。</p> <p>文章描述了对一名年轻患者的临床观察。第二次分娩后，患者发现了肩胛骨之间的颈部出现剧烈疼痛。随后，在出现症状两个月后，患者患上了肺炎，并对抗生素治疗产生了积极反应。两个月后，她首次发现了反复腹水和胃肠道症状。检查发现了卵巢病变、腹膜转移癌征候以及肺部病灶。然而，腹膜转移癌的临床表现并不典型，而且肺部有特殊病变，因此怀疑是多部位结核。通过腹腔镜检查和受影响组织的活检，以及随后的组织学和实验室检查，确诊为Mycobacterium tuberculosis。</p> <p>该病例表明，在确定年轻女性患者腹水的病因时，必须使用所有可用的诊断方法，以便对特异性病因和肿瘤性病因进行鉴别诊断。</p></trans-abstract><kwd-group xml:lang="en"><kwd>tuberculosis of multiple localizations</kwd><kwd>peritoneal tuberculosis</kwd><kwd>tuberculosis of abdominal organs</kwd><kwd>peritoneal carcinomatosis</kwd><kwd>ascites</kwd><kwd>case report</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>туберкулёз множественных локализаций</kwd><kwd>абдоминальный туберкулёз</kwd><kwd>туберкулёз органов брюшной полости</kwd><kwd>карциноматоз брюшины</kwd><kwd>асцит</kwd><kwd>описание случая</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>多部位结核</kwd><kwd>腹部结核</kwd><kwd>腹腔结核</kwd><kwd>腹膜转移癌</kwd><kwd>腹水</kwd><kwd>病例介绍</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution xml:lang="ru">Департамент здравоохранения города Москвы</institution></institution-wrap><institution-wrap><institution xml:lang="en">Moscow Health Care Department</institution></institution-wrap><institution-wrap><institution xml:lang="zh">Moscow Health Care Department</institution></institution-wrap></funding-source><award-id>123031400009-1</award-id></award-group><funding-statement xml:lang="en">This paper was prepared by a group of authors as a part of the research and development effort titled “Opportunistic screening of high-profile and other common diseases”, No. 123031400009-1”, (USIS No. 123031400009-1 ) in accordance with the Order No. 1196 dated December 21, 2022 "On approval of state assignments funded by means of allocations from the budget of the city of Moscow to the state budgetary (autonomous) institutions subordinate to the Moscow Health Care Department, for 2023 and the planned period of 2024 and 2025" issued by the Moscow Health Care Department</funding-statement><funding-statement xml:lang="ru">Данная статья подготовлена авторским коллективом в рамках НИР «Оппортунистический скрининг социально значимых и иных распространённых заболеваний», (№ ЕГИСУ: № 123031400009-1 ) в соответствии с Приказом от 21.12.2022 г. № 1196 "Об утверждении государственных заданий, финансовое обеспечение которых осуществляется за счет средств бюджета города Москвы государственным бюджетным (автономным) учреждениям подведомственным Департаменту здравоохранения города Москвы, на 2023 год и плановый период 2024 и 2025 годов" Департамента здравоохранения города Москвы.</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Hopewell PC, Jasmer RM. 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