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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Digital Diagnostics</journal-id><journal-title-group><journal-title xml:lang="en">Digital Diagnostics</journal-title><trans-title-group xml:lang="ru"><trans-title>Digital Diagnostics</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Digital Diagnostics</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2712-8490</issn><issn publication-format="electronic">2712-8962</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">641570</article-id><article-id pub-id-type="doi">10.17816/DD641570</article-id><article-id pub-id-type="edn">VQQVDQ</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>科学评论</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Diagnostic and prognostic relevance of imaging-based body composition analysis in postmenopausal women: a review</article-title><trans-title-group xml:lang="ru"><trans-title>Диагностическая и прогностическая значимость анализа композиционного состава тела с применением методов медицинской визуализации у женщин в постменопаузе: обзор</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>采用医学影像学方法分析绝经后女性身体成分的诊断与预后意义：综述</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6483-7139</contrib-id><name-alternatives><name xml:lang="en"><surname>Aparisi Gómez</surname><given-names>Maria P.</given-names></name><name xml:lang="ru"><surname>Aparisi Gómez</surname><given-names>Maria Pilar</given-names></name><name xml:lang="zh"><surname>Aparisi Gómez</surname><given-names>Maria P.</given-names></name></name-alternatives><address><country country="NZ">New Zealand</country></address><email>pilar.aparisi@tewhatuora.govt.nz</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1275-6265</contrib-id><name-alternatives><name xml:lang="en"><surname>Petrera</surname><given-names>Miriana R.</given-names></name><name xml:lang="ru"><surname>Petrera</surname><given-names>Miriana Rosaria</given-names></name><name xml:lang="zh"><surname>Petrera</surname><given-names>Miriana R.</given-names></name></name-alternatives><address><country country="IT">Italy</country></address><email>mirianapetrera@gmail.com</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7187-1116</contrib-id><name><surname>Santoro</surname><given-names>Aurelia</given-names></name><address><country country="IT">Italy</country></address><bio xml:lang="en"><p>MD, PhD, Associate Professor</p></bio><bio xml:lang="ru"><p>доцент</p></bio><bio xml:lang="zh"><p>MD, PhD, Associate Professor</p></bio><email>aurelia.santoro@unibo.it</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7040-6466</contrib-id><name-alternatives><name xml:lang="en"><surname>Petroni</surname><given-names>Maria L.</given-names></name><name xml:lang="ru"><surname>Petroni</surname><given-names>Maria Letizia</given-names></name><name xml:lang="zh"><surname>Petroni</surname><given-names>Maria L.</given-names></name></name-alternatives><address><country country="IT">Italy</country></address><bio xml:lang="en"><p>MD, Associate Professor</p></bio><bio xml:lang="ru"><p>доцент</p></bio><bio xml:lang="zh"><p>MD, Associate Professor</p></bio><email>marialetizia.petroni@unibo.it</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5306-0985</contrib-id><name><surname>Gasperini</surname><given-names>Chiara</given-names></name><address><country country="IT">Italy</country></address><email>chiara.gasperini@unibo.it</email><xref ref-type="aff" rid="aff5"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9841-6386</contrib-id><name><surname>Franceschi</surname><given-names>Claudio</given-names></name><address><country country="IT">Italy</country></address><bio xml:lang="en"><p>MD, Professor</p></bio><bio xml:lang="ru"><p>профессор</p></bio><bio xml:lang="zh"><p>MD, Professor</p></bio><email>claudio.franceschi@unibo.it</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2407-9860</contrib-id><name><surname>Marchesini</surname><given-names>Giulio</given-names></name><address><country country="IT">Italy</country></address><bio xml:lang="en"><p>MD, Professor</p></bio><bio xml:lang="ru"><p>профессор</p></bio><bio xml:lang="zh"><p>MD, Professor</p></bio><email>giulio.marchesini@unibo.it</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4325-8330</contrib-id><name><surname>Guglielmi</surname><given-names>Giuseppe</given-names></name><address><country country="IT">Italy</country></address><bio xml:lang="en"><p>MD, Professor</p></bio><bio xml:lang="ru"><p>профессор</p></bio><bio xml:lang="zh"><p>MD, Professor</p></bio><email>giuseppe.guglielmi@unifg.it</email><xref ref-type="aff" rid="aff6"/><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2659-4535</contrib-id><name><surname>Bazzocchi</surname><given-names>Alberto</given-names></name><address><country country="IT">Italy</country></address><email>abazzocchi@gmail.com</email><xref ref-type="aff" rid="aff5"/></contrib></contrib-group><aff id="aff1"><institution>Te Toka Tumai Auckland (Auckland District Health Board)</institution></aff><aff id="aff2"><institution>Waipapa Taumata Rau — University of Auckland</institution></aff><aff-alternatives id="aff3"><aff><institution xml:lang="en">National Institute for Infectious Disease “Lazzaro Spallanzani”</institution></aff><aff><institution xml:lang="ru">National Institute for Infectious Disease «Lazzaro Spallanzani»</institution></aff><aff><institution xml:lang="zh">National Institute for Infectious Disease “Lazzaro Spallanzani”</institution></aff></aff-alternatives><aff id="aff4"><institution>University of Bologna, Sant'Orsola-Malpighi Hospital</institution></aff><aff id="aff5"><institution>IRCCS Istituto Ortopedico Rizzoli</institution></aff><aff id="aff6"><institution>University of Foggia</institution></aff><aff-alternatives id="aff7"><aff><institution xml:lang="en">“IRCCS Casa Sollievo della Sofferenza” Hospital</institution></aff><aff><institution xml:lang="ru">«IRCCS Casa Sollievo della Sofferenza» Hospital</institution></aff><aff><institution xml:lang="zh">“IRCCS Casa Sollievo della Sofferenza” Hospital</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-12-16" publication-format="electronic"><day>16</day><month>12</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-12-29" publication-format="electronic"><day>29</day><month>12</month><year>2025</year></pub-date><volume>6</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>583</fpage><lpage>602</lpage><history><date date-type="received" iso-8601-date="2024-11-05"><day>05</day><month>11</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2025-07-07"><day>07</day><month>07</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-вектор</copyright-holder><copyright-holder xml:lang="zh">Eco-Vector</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://jdigitaldiagnostics.com/DD/article/view/641570">https://jdigitaldiagnostics.com/DD/article/view/641570</self-uri><abstract xml:lang="en"><p>The article presents an assessment of body composition markers measured by imaging in clinical practice for postmenopausal and aging women. Body composition changes with aging and is specifically affected by endocrinological changes occurring with menopause. Several imaging markers have been proposed and used in the assessment of body composition status. The associations of different imaging markers with cardiometabolic risk and risks for other diseases, with impact on morbidity/mortality, functional impairment, and frailty, are discussed. The imaging markers confirmed by evidence and are applicable to clinical practice are highlighted. With this purpose, the current level of evidence in the literature on reliability and potential associations of each relevant marker was reviewed.</p> <p>This review describes what can and should be done with available imaging tools (e.g., dual-energy x-ray absorptiometry, ultrasound, computed tomography, and magnetic resonance imaging) in dedicated and opportunistic settings (i.e., tests for assessing body composition vs those for other clinical reasons but wherein exploitation of imaging data is possible) to improve the management and understanding of lifestyle needs of postmenopausal women and thus to prevent or decrease unhealthy aging and rate of women with aging-related diseases.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлена оценка маркёров композиционного состава тела у женщин в период постменопаузы и старения, полученных с помощью методов медицинской визуализации в условиях реальной клинической практики. С возрастом состав тела меняется, что особенно заметно в период менопаузы, когда в организме женщины происходят эндокринные изменения. В научной практике для оценки композиционного состава тела используют определённые визуализационные маркёры. В настоящем обзоре проанализированы связи различных визуализационных показателей с риском развития кардиометаболических нарушений и других заболеваний с учётом их влияния на частоту развития сопутствующих заболеваний и смертность, развитие функциональных нарушений и старческой астении. Особое внимание уделено визуализационным маркёрам, диагностическая эффективность которых подтверждена, что позволяет их использовать в условиях клинической практики. С этой целью проанализированы публикации, содержащие актуальные доказательные данные о надёжности исследуемых маркёров и их возможной связи с другими факторами.</p> <p>В обзоре рассмотрены возможности для улучшения тактики ведения женщин в постменопаузе, изучения их жизненных потребностей и профилактики или снижения степени выраженности неблагоприятного старения и частоты развития возрастных заболеваний посредством применения существующих методов медицинской визуализации (например, двухэнергетической рентгеновской абсорбциометрии, ультразвукового исследования, компьютерной томографии и магнитно-резонансной томографии) при целенаправленном исследовании композиционного состава тела и проведении исследований по другим клиническим показаниям с получением соответствующих данных.</p></trans-abstract><trans-abstract xml:lang="zh"><p>本文通过医学影像技术，在真实临床实践中对绝经后及衰老期女性身体成分标志物进行了评估。随着年龄增长，人体成分会发生变化，这种变化在更年期尤为明显，此时女性体内会发生内分泌变化。在科学实践中，采用特定的影像学标志物来评估人体成分构成。本综述分析了各种影像学指标与心代谢紊乱及其他疾病风险之间的关联，同时考虑了这些指标对并发症发生率、死亡率、功能障碍及老年衰弱症的影响。特别关注了诊断有效性得到证实的影像学标志物，这些标志物可在临床实践中应用。为此，本综述分析了包含研究标志物可靠性及其与其他因素潜在关联的最新证据数据的文献。</p> <p>本综述探讨了改善绝经后女性管理策略的可能性，研究其生活需求，并通过应用现有医学影像技术（例如双能X射线吸收测定法、超声检查、计算机断层扫描和磁共振成像）来预防或减轻不良衰老程度及年龄相关疾病的发生率。（例如双能X射线吸收测定法、超声检查、计算机断层扫描和磁共振成像），有针对性地研究身体成分构成，并针对其他临床指征开展研究以获取相关数据。</p></trans-abstract><kwd-group xml:lang="en"><kwd>postmenopause</kwd><kwd>sarcopenia</kwd><kwd>metabolic disorders</kwd><kwd>aging</kwd><kwd>body composition</kwd><kwd>absorptiometry</kwd><kwd>diagnostic imaging</kwd><kwd>review</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>постменопауза</kwd><kwd>саркопения</kwd><kwd>метаболические нарушения</kwd><kwd>старение</kwd><kwd>состав тела</kwd><kwd>двухэнергетическая рентгеновская абсорбциометрия</kwd><kwd>диагностическая визуализация</kwd><kwd>обзор</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>绝经后</kwd><kwd>肌少症</kwd><kwd>代谢紊乱</kwd><kwd>衰老</kwd><kwd>体成分</kwd><kwd>双能X线吸收测定法</kwd><kwd>诊断成像</kwd><kwd>综述</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Thibault R, Genton L, Pichard C. 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