Digital DiagnosticsDigital DiagnosticsDigital DiagnosticsDigital Diagnostics2712-84902712-8962Eco-Vector69052110.17816/DD690521Case reportsКлинические случаи и серии клинических случаев临床病例及临床病例的系列Beyond Skin Deep: Unraveling Breast Neurofibromatosis - A Captivating Case Reporthttps://orcid.org/0009-0009-2808-5708BalbinoMarinamarinabalbino93@gmail.comhttps://orcid.org/0009-0002-1526-5047ManuelaMontatoremanuela.montatore@unifg.ithttps://orcid.org/0009-0004-4289-3289FedericaMasinofedericamasino@gmail.comCarpagnanoFrancesca Annac.francesca1991@gmail.comhttps://orcid.org/0000-0002-4325-8330GuglielmiGiuseppe
Italy

Medical Doctor, Full Professor of Radiology.

Department of Clinical and Experimental Medicine.

Доктор медицины, профессор.

Кафедра клинической и экспериментальной медицины.

giuseppe.guglielmi@unifg.itDepartment of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, 71122 Foggia, Italy.Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, 71122 Foggia, Italy.Breast Unit, Dimiccoli” Hospital, Viale Ippocrate 15, 70051, Barletta (BT), Italy.University of Foggia07042026711709202520012026Copyright ©; , Eco-VectorCopyright ©; , Эко-векторCopyright ©; , Eco-VectorEco-VectorЭко-векторEco-Vectorhttps://creativecommons.org/licenses/by-nc-nd/4.0https://jdigitaldiagnostics.com/DD/article/view/690521

Neurofibromatosis type 1 (NF1) is a genetic disorder characterized by the growth of tumors on nerve tissue, known as neurofibromas. Although neurofibromas most commonly affect various parts of the body, their occurrence in the breast is relatively rare. We present a case of a 55yearold female with a known history of NF1 who presented with a palpable mass in her left breast. Imaging studies revealed heterogeneous lesions consistent with neurofibroma. Histopathological examination and surgical excision confirmed the diagnosis. The patient experienced discomfort and aesthetic concerns due to the enlarging mass, prompting surgical intervention. This case highlights the importance of including neurofibromatosis in the differential diagnosis of breast masses in individuals with NF1. Management strategies, including surveillance and surgical excision, are discussed in relation to improving patient outcomes and quality of life.

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