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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Digital Diagnostics</journal-id><journal-title-group><journal-title xml:lang="en">Digital Diagnostics</journal-title><trans-title-group xml:lang="ru"><trans-title>Digital Diagnostics</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Digital Diagnostics</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2712-8490</issn><issn publication-format="electronic">2712-8962</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">70170</article-id><article-id pub-id-type="doi">10.17816/DD70170</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>科学评论</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Magnetic resonance imaging radiomics in prostate cancer radiology: what is currently known?</article-title><trans-title-group xml:lang="ru"><trans-title>Радиомика магнитно-резонансной томографии при раке предстательной железы: что известно в настоящее время?</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>前列腺癌磁共振成像的放射组学： 目前已知的是什么？</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1072-2202</contrib-id><contrib-id contrib-id-type="spin">4841-3234</contrib-id><name-alternatives><name xml:lang="en"><surname>Gelezhe</surname><given-names>Pavel B.</given-names></name><name xml:lang="ru"><surname>Гележе</surname><given-names>Павел Борисович</given-names></name><name xml:lang="zh"><surname>Gelezhe</surname><given-names>Pavel B.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Med.)</p></bio><email>gelezhe.pavel@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2681-9378</contrib-id><contrib-id contrib-id-type="spin">3306-1387</contrib-id><name-alternatives><name xml:lang="en"><surname>Blokhin</surname><given-names>Ivan A.</given-names></name><name xml:lang="ru"><surname>Блохин</surname><given-names>Иван Андреевич</given-names></name><name xml:lang="zh"><surname>Blokhin</surname><given-names>Ivan A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>i.blokhin@npcmr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2585-0864</contrib-id><contrib-id contrib-id-type="spin">4790-0416</contrib-id><name-alternatives><name xml:lang="en"><surname>Semenov</surname><given-names>Serafim S.</given-names></name><name xml:lang="ru"><surname>Семенов</surname><given-names>Серафим Сергеевич</given-names></name><name xml:lang="zh"><surname>Semenov</surname><given-names>Serafim S.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><bio xml:lang="zh"><p>MD</p></bio><email>s.semenov@npcmr.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9285-4764</contrib-id><name><surname>Caruso</surname><given-names>Damiano</given-names></name><address><country country="IT">Italy</country></address><bio xml:lang="en"><p>MD, PhD, Department of Surgical and Medical Sciences and Translational Medicine, Radiology Unit</p></bio><bio xml:lang="ru"><p>отделение хирургических и медицинских наук и трансляционной медицины; отделение радиологии</p></bio><bio xml:lang="zh"><p>MD, PhD, Department of Surgical and Medical Sciences and Translational Medicine, Radiology Unit</p></bio><email>dcaruso85@gmail.com</email><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff5"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Center for Diagnostics and Telemedicine</institution></aff><aff><institution xml:lang="ru">Научно-практический клинический центр диагностики и телемедицинских технологий Департамента здравоохранения г. Москвы</institution></aff><aff><institution xml:lang="zh">Moscow Center for Diagnostics and Telemedicine</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">European Medical Center</institution></aff><aff><institution xml:lang="ru">Европейский медицинский центр</institution></aff><aff><institution xml:lang="zh">European Medical Center</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Moscow Clinical Scientific Center named after A.S. Loginov</institution></aff><aff><institution xml:lang="ru">Московский клинический научно-практический центр имени А.С. Логинова</institution></aff><aff><institution xml:lang="zh">Moscow Clinical Scientific Center named after A.S. Loginov</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Sapienza University of Rome</institution></aff><aff><institution xml:lang="ru">Римский университет Сапиенца</institution></aff><aff><institution xml:lang="zh">Sapienza University of Rome</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Sant’Andrea University Hospital</institution></aff><aff><institution xml:lang="ru">Больница Сант Андреа</institution></aff><aff><institution xml:lang="zh">Sant’Andrea University Hospital</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2021-12-06" publication-format="electronic"><day>06</day><month>12</month><year>2021</year></pub-date><pub-date date-type="pub" iso-8601-date="2021-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2021</year></pub-date><volume>2</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>441</fpage><lpage>452</lpage><history><date date-type="received" iso-8601-date="2021-05-03"><day>03</day><month>05</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-11-27"><day>27</day><month>11</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Gelezhe P.B., Blokhin I.A., Semenov S.S., Caruso D.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Гележе П.Б., Блохин И.А., Семенов С.С., Caruso D.</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2021, Gelezhe P., Blokhin I., Semenov S., Caruso D.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Gelezhe P.B., Blokhin I.A., Semenov S.S., Caruso D.</copyright-holder><copyright-holder xml:lang="ru">Гележе П.Б., Блохин И.А., Семенов С.С., Caruso D.</copyright-holder><copyright-holder xml:lang="zh">Gelezhe P., Blokhin I., Semenov S., Caruso D.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://jdigitaldiagnostics.com/DD/article/view/70170">https://jdigitaldiagnostics.com/DD/article/view/70170</self-uri><abstract xml:lang="en"><p>Diagnostic and treatment approaches in prostate cancer rely on a combination of magnetic resonance imaging and histological data.</p> <p>This study aimed to introduce the basics of the current diagnostic approach in prostate cancer with a focus on texture analysis.</p> <p>Texture analysis evaluates the relationships between image pixels using mathematical methods, which provide additional information. First-order texture analysis of features can have greater clinical reproducibility than higher-order texture features. Textural features that are extracted from diffusion coefficient maps have shown the greatest clinical relevance. Future research should focus on integrating machine learning methods to facilitate the use of texture analysis in clinical practice.</p> <p>The development of automated segmentation methods is required to reduce the likelihood of including normal tissue in the area of interest. Texture analysis allows the noninvasive separation of patients into groups in terms of possible treatment options. Currently, few clinical studies reported on the differential diagnosis of clinically significant prostate cancer, including the Gleason and International Society of Urological Pathology grading. Large prospective studies are required to verify the diagnostic potential of textural features.</p></abstract><trans-abstract xml:lang="ru"><p>Подходы к диагностике и лечению рака предстательной железы опираются на комбинацию данных магнитно-резонансной томографии и гистологических данных.</p> <p>Цель данного обзора ― введение читателя в основы современного диагностического подхода к раку предстательной железы при помощи магнитно-резонансной томографии с фокусом на текстурный анализ цифровых медицинских изображений.</p> <p>Текстурный анализ позволяет оценить взаимосвязи между пикселями изображения с помощью математических методов, что даёт дополнительную информацию, в первую очередь о внутриопухолевой гетерогенности. Текстурный анализ признаков первого порядка может иметь бό́льшую клиническую воспроизводимость, чем текстурные характеристики более высокого порядка. Текстурные особенности, извлечённые из карт коэффициента диффузии, показали наибольшую клиническую значимость.</p> <p>Будущие исследования должны быть направлены на интеграцию методов машинного обучения для облегчения использования текстурного анализа в клинической практике. Требуется развитие автоматизированных методов сегментации для уменьшения вероятности включения нормальных тканей в области интереса и ускорения получения результатов анализа. Для проверки диагностического потенциала текстурных признаков требуются крупные проспективные исследования.</p></trans-abstract><trans-abstract xml:lang="zh"><p>前列腺癌的诊断和治疗方法依赖于磁共振成像和组织学数据的结合。</p> <p>这篇综述的目的是向读者介绍利用磁共振成像对前列腺癌进行现代诊断的基本方法，重点是数字医学图像的纹理分析。</p> <p>纹理分析使使用数学方法评估图像像素之间的关系成为可能，这提供了额外的信息，主要是关于肿瘤内异质性的信息。一阶特征的纹理分析可能比高阶纹理特征具有更大的临床再现性。从扩散系数图中提取的纹理特征具有最大的临床意义。</p> <p>未来的研究应侧重于整合机器学习技术，以促进纹理分析在临床实践中的应用。需要开发自动分割方法，以降低将正常组织纳入感兴趣区域的可能性，并加快分析结果的传递。为了测试纹理特征的诊断潜力，需要进行大规模的前瞻性研究。</p></trans-abstract><kwd-group xml:lang="en"><kwd>prostate cancer</kwd><kwd>magnetic resonance imaging</kwd><kwd>MRI</kwd><kwd>radiomics</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак предстательной железы</kwd><kwd>магнитно-резонансная томография</kwd><kwd>МРТ</kwd><kwd>радиомика</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>前列腺癌</kwd><kwd>磁共振成像</kwd><kwd>磁共振成像</kwd><kwd>无线电麦克风</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Turkbey B, Rosenkrantz AB, Haider MA, et al. Prostate imaging reporting and data system version 2.1: 2019 update of prostate imaging reporting and data system version 2. Eur Urol. 2019;76(3):340–351. doi: 10.1016/j.eururo.2019.02.033</mixed-citation><mixed-citation xml:lang="ru">Turkbey B., Rosenkrantz A.B., Haider M.A., et al. Prostate imaging reporting and data system version 2.1: 2019 update of prostate imaging reporting and data system version 2 // European Urology. 2019. Vol. 76, N 3. P. 340–351. doi: 10.1016/j.eururo.2019.02.033</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Kasivisvanathan V, Rannikko AS, Borghi M, et al. MRI-targeted or standard biopsy for prostate-cancer diagnosis. N Engl J Med. 2018;378(19):1767–1777. doi: 10.1056/NEJMoa1801993</mixed-citation><mixed-citation xml:lang="ru">Kasivisvanathan V., Rannikko A.S., Borghi M., et al. MRI-targeted or standard biopsy for prostate-cancer diagnosis // N Engl J Med. 2018. Vol. 378, N 19. P. 1767–1777. doi: 10.1056/NEJMoa1801993</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Ahmed HU, El-Shater Bosaily A, Brown LC, et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study. The Lancet. 2017;389(10071):815–822. doi: 10.1016/S0140-6736(16)32401-1</mixed-citation><mixed-citation xml:lang="ru">Ahmed H.U., El-Shater Bosaily A., Brown L.C., et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study // The Lancet. 2017. Vol. 389, N 10071. P. 815–822. doi: 10.1016/S0140-6736(16)32401-1</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Purysko AS, Rosenkrantz AB, Barentsz JO, et al. PI-RADS version 2: a pictorial update. Radiographics. 2016;36(5):1354–1372. doi: 10.1148/rg.2016150234</mixed-citation><mixed-citation xml:lang="ru">Purysko A.S., Rosenkrantz A.B., Barentsz J.O., et al. PI-RADS version 2: a pictorial update // Radiographics. 2016. Vol. 36, N 5. P. 1354–1372. doi: 10.1148/rg.2016150234</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Patel N, Henry A, Scarsbrook A. The value of MR textural analysis in prostate cancer. Clin Radiol. 2019;74(11):876–885. doi: 10.1016/j.crad.2018.11.007</mixed-citation><mixed-citation xml:lang="ru">Patel N., Henry A., Scarsbrook A. The value of MR textural analysis in prostate cancer // Clin Radiol. 2019. Vol. 74, N 11. P. 876–885. doi: 10.1016/j.crad.2018.11.007</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Sala E, Mema E, Himoto Y, et al. Unravelling tumour heterogeneity using next-generation imaging: radiomics, radiogenomics, and habitat imaging. Clin Radiol. 2017;72(1):3–10. doi: 10.1016/j.crad.2016.09.013</mixed-citation><mixed-citation xml:lang="ru">Sala E., Mema E., Himoto Y., et al. Unravelling tumour heterogeneity using next-generation imaging: radiomics, radiogenomics, and habitat imaging // Clin Radiol. 2017. Vol. 72, N 1. P. 3–10. doi: 10.1016/j.crad.2016.09.013</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Gleason DF. Classification of prostatic carcinomas. Cancer Chemother Rep. 1966;50(3):125–128.</mixed-citation><mixed-citation xml:lang="ru">Gleason D.F. Classification of prostatic carcinomas // Cancer Chemother Rep. 1966. Vol. 50, N 3. P. 125–128.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Young JC, Jeong KK, Kim N, et al. Functional MR imaging of prostate cancer. Radiographics. 2007;27(1): 63–75. doi: 10.1148/rg.271065078</mixed-citation><mixed-citation xml:lang="ru">Young J.C., Jeong K.K., Kim N., et al. Functional MR imaging of prostate cancer // Radiographics. 2007. Vol. 27, N 1. P. 63–75. doi: 10.1148/rg.271065078</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Nketiah G, Elschot M, Kim E, et al. T2-weighted MRI-derived textural features reflect prostate cancer aggressiveness: preliminary results. Eur Radiol. 2017;27(7):3050–3059. doi: 10.1007/s00330-016-4663-1</mixed-citation><mixed-citation xml:lang="ru">Nketiah G., Elschot M., Kim E., et al. T2-weighted MRI-derived textural features reflect prostate cancer aggressiveness: preliminary results // Eur Radiol. 2017. Vol. 27, N 7. P. 3050–3059. doi: 10.1007/s00330-016-4663-1</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Morone M, Bali MA, Tunariu N, et al. Whole-body MRI: current applications in oncology. AJR Am J Roentgenol. 2017;209(6):W336–W349. doi: 10.2214/AJR.17.17984</mixed-citation><mixed-citation xml:lang="ru">Morone M., Bali M.A., Tunariu N., et al. Whole-body MRI: current applications in oncology // AJR Am J Roentgenol. 2017. Vol. 209, N 6. P. W336–W349. doi: 10.2214/AJR.17.17984</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Nowak J, Malzahn U, Baur AD, et al. The value of ADC, T2 signal intensity, and a combination of both parameters to assess Gleason score and primary Gleason grades in patients with known prostate cancer. Acta Radiol. 2016;57(1):107–114. doi: 10.1177/0284185114561915</mixed-citation><mixed-citation xml:lang="ru">Nowak J., Malzahn U., Baur A.D., et al. The value of ADC, T2 signal intensity, and a combination of both parameters to assess Gleason score and primary Gleason grades in patients with known prostate cancer // Acta Radiol. 2016. Vol. 57, N 1. P. 107–114. doi: 10.1177/0284185114561915</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Gillies RJ, Kinahan PE, Hricak H. Radiomics: Images are more than pictures, they are data. Radiology. 2016;278(2):563–577. doi: 10.1148/radiol.2015151169</mixed-citation><mixed-citation xml:lang="ru">Gillies R.J., Kinahan P.E., Hricak H. Radiomics: Images are more than pictures, they are data // Radiology. 2016. Vol. 278, N 2. P. 563–577. doi: 10.1148/radiol.2015151169</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Summers RM. Texture analysis in radiology: Does the emperor have no clothes? Abdom Radiol. 2017;42(2):342–345. doi: 10.1007/s00261-016-0950-1</mixed-citation><mixed-citation xml:lang="ru">Summers R.M. Texture analysis in radiology: does the emperor have no clothes? // Abdominal Radiology. 2017. Vol. 42, N 2. P. 342–345. doi: 10.1007/s00261-016-0950-1</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Bleker J, Kwee TC, Dierckx RA, et al. Multiparametric MRI and auto-fixed volume of interest-based radiomics signature for clinically significant peripheral zone prostate cancer. Eur Radiol. 2020;30(3):1313–1324. doi: 10.1007/s00330-019-06488-y</mixed-citation><mixed-citation xml:lang="ru">Bleker J., Kwee T.C., Dierckx R.A., et al. Multiparametric MRI and auto-fixed volume of interest-based radiomics signature for clinically significant peripheral zone prostate cancer // Eur radiol. 2020. Vol. 30, N 3. P. 1313–1324. doi: 10.1007/s00330-019-06488-y</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Scalco E, Rizzo G. Texture analysis of medical images for radiotherapy applications. Br J Radiol. 2017;90(1070):20160642. doi: 10.1259/bjr.20160642</mixed-citation><mixed-citation xml:lang="ru">Scalco E., Rizzo G. Texture analysis of medical images for radiotherapy applications // Br J Radiol. 2017. Vol. 90, N 1070. P. 20160642. doi: 10.1259/bjr.20160642</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">Wibmer A, Hricak H, Gondo T, et al. Haralick texture analysis of prostate MRI: utility for differentiating non-cancerous prostate from prostate cancer and differentiating prostate cancers with different Gleason scores. Eur Radiol. 2015;25(10):2840–2850. doi: 10.1007/s00330-015-3701-8</mixed-citation><mixed-citation xml:lang="ru">Wibmer A., Hricak H., Gondo T., et al. Haralick texture analysis of prostate MRI: utility for differentiating non-cancerous prostate from prostate cancer and differentiating prostate cancers with different Gleason scores // Eur Radiol. 2015. Vol. 25, N 10. P. 2840–2850. doi: 10.1007/s00330-015-3701-8</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">Losnegard A, Reisæter L, Halvorsen OJ, et al. Magnetic resonance radiomics for prediction of extraprostatic extension in non-favorable intermediateand high-risk prostate cancer patients. Acta Radiol. 2020;61(11):1570–1579. doi: 10.1177/0284185120905066</mixed-citation><mixed-citation xml:lang="ru">Losnegard A., Reisæter L., Halvorsen O.J., et al. Magnetic resonance radiomics for prediction of extraprostatic extension in non-favorable intermediateand high-risk prostate cancer patients // Acta Radiol. 2020. Vol. 61, N 11. P. 1570–1579. doi: 10.1177/0284185120905066</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">Larue RT, Defraene G, Ruysscher DD, et al. Quantitative radiomics studies for tissue characterization: A review of technology and methodological procedures. Br J Radiol. 2017;90(1070):20160665. doi: 10.1259/bjr.20160665</mixed-citation><mixed-citation xml:lang="ru">Larue R.T., Defraene G., Ruysscher D., et al. Quantitative radiomics studies for tissue characterization: a review of technology and methodological procedures // Br J Radiol. 2017. Vol. 90, N 1070. P. 20160665. doi: 10.1259/bjr.20160665</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">Court LE, Fave X, Mackin D, et al. Computational resources for radiomics. Translational Cancer Research. 2016;5(4):340–348. doi: 10.21037/tcr.2016.06.17</mixed-citation><mixed-citation xml:lang="ru">Court L.E., Fave X., Mackin D., et al. Computational resources for radiomics // Translational Cancer Research. 2016. Vol. 5, N 4. P. 340–348. doi: 10.21037/tcr.2016.06.17</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">Laplacian of Gaussian Filter [Electronic resource]. Available from: https://academic.mu.edu/phys/matthysd/web226/Lab02.htm. Accessed: 21.11.2021.</mixed-citation><mixed-citation xml:lang="ru">Laplacian of Gaussian Filter [электронный ресурс]. Режим доступа: https://academic.mu.edu/phys/matthysd/web226/Lab02.htm. Дата обращения: 21.11.2021.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">Fehr D, Veeraraghavan H, Wibmer A, et al. Automatic classification of prostate cancer Gleason scores from multiparametric magnetic resonance. Proc Natl Acad Sci U S A. 2015;112(46):E6265–E6273. doi: 10.1073/pnas.1505935112</mixed-citation><mixed-citation xml:lang="ru">Fehr D., Veeraraghavan H., Wibmer A., et al. Automatic classification of prostate cancer Gleason scores from multiparametric magnetic resonance images // Proceedings of the National Academy of Sciences of the United States of America. 2015. Vol. 112, N 46. P. E6265–E6273. doi: 10.1073/pnas.1505935112</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">Sidhu HS, Benigno S, Ganeshan B, et al. Textural analysis of multiparametric MRI detects transition zone prostate cancer. Eur Radiol. 2017;27(6):2348–2358. doi: 10.1007/s00330-016-4579-9</mixed-citation><mixed-citation xml:lang="ru">Sidhu H.S., Benigno S., Ganeshan B., et al. Textural analysis of multiparametric MRI detects transition zone prostate cancer // Eur Radiol. 2017. Vol. 27, N 6. P. 2348–2358. doi: 10.1007/s00330-016-4579-9</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">Vignati A, Mazzetti S, Giannini V, et al. Texture features on T2-weighted magnetic resonance imaging: new potential biomarkers for prostate cancer aggressiveness. Phys Med Biol. 2015;60(7):2685–2701. doi: 10.1088/0031-9155/60/7/2685</mixed-citation><mixed-citation xml:lang="ru">Vignati A., Mazzetti S., Giannini V., et al. Texture features on T2-weighted magnetic resonance imaging: new potential biomarkers for prostate cancer aggressiveness // Phys Med Biol. 2015. Vol. 60, N 7. P. 2685–2701. doi: 10.1088/0031-9155/60/7/2685</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">Sierra PS, Damodaran S, Jarrard D. Clinical and pathologic factors predicting reclassification in active surveillance cohorts. Int Braz J Urol. 2018;44(3):440. doi: 10.1590/S1677-5538.IBJU.2017.0320</mixed-citation><mixed-citation xml:lang="ru">Sierra P.S., Damodaran S., Jarrard D. Clinical and pathologic factors predicting reclassification in active surveillance cohorts // Int Braz J Urol. 2018. Vol. 44, N 3. P. 440. doi: 10.1590/S1677-5538.IBJU.2017.0320</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">Murciano-Goroff YR, Wolfsberger LD, Parekh A, et al. Variability in MRI vs. ultrasound measures of prostate volume and its impact on treatment recommendations for favorable-risk prostate cancer patients: a case series. Radiat Oncol. 2014;9:200. doi: 10.1186/1748-717X-9-200</mixed-citation><mixed-citation xml:lang="ru">Murciano-Goroff Y.R., Wolfsberger L.D., Parekh A., et al. Variability in MRI vs. ultrasound measures of prostate volume and its impact on treatment recommendations for favorable-risk prostate cancer patients: a case series // Radiat Oncol. 2014. Vol. 9. P. 200. doi: 10.1186/1748-717X-9-200</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><citation-alternatives><mixed-citation xml:lang="en">Engels RR, Israël B, Padhani AR, et al. Multiparametric magnetic resonance imaging for the detection of clinically significant prostate cancer: what urologists need to know. Part 1: acquisition. Eur Urology. 2020;77(4):457–468. doi: 10.1016/j.eururo.2019.09.021</mixed-citation><mixed-citation xml:lang="ru">Engels R.R., Israël B., Padhani A.R., et al. Multiparametric magnetic resonance imaging for the detection of clinically significant prostate cancer: what urologists need to know. Part 1: acquisition // Eur Urology. 2020. Vol. 77, N 4. P. 457–468. doi: 10.1016/j.eururo.2019.09.021</mixed-citation></citation-alternatives></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">Min X, Li M, Dong D, et al. Multi-parametric MRI-based radiomics signature for discriminating between clinically significant and insignificant prostate cancer: cross-validation of a machine learning method. Eur J Radiol. 2019;115:16–21. doi: 10.1016/j.ejrad.2019.03.010</mixed-citation><mixed-citation xml:lang="ru">Min X., Li M., Dong D., et al. Multi-parametric MRI-based radiomics signature for discriminating between clinically significant and insignificant prostate cancer: cross-validation of a machine learning method // Eur J Radiol. 2019. Vol. 115. P. 16–21. doi: 10.1016/j.ejrad.2019.03.010</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">Westphalen AC, McCulloch CE, Anaokar JM, et al. Variability of the positive predictive value of PI-RADS for prostate MRI across 26 centers: experience of the Society of Abdominal Radiology Prostate Cancer Disease-focused Panel. Radiology. 2020;296(1):76–84. doi: 10.1148/radiol.2020190646</mixed-citation><mixed-citation xml:lang="ru">Westphalen A.C., McCulloch C.E., Anaokar J.M., et al. Variability of the positive predictive value of PI-RADS for prostate MRI across 26 centers: experience of the Society of Abdominal Radiology Prostate Cancer Disease-focused Panel // Radiology. 2020. Vol. 296, N 1. P. 76–84. doi: 10.1148/radiol.2020190646</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><citation-alternatives><mixed-citation xml:lang="en">Xu L, Zhang G, Zhao L, et al. Radiomics based on multiparametric magnetic resonance imaging to predict extraprostatic extension of prostate cancer. Front Oncol. 2020;10:940. doi: 10.3389/fonc.2020.00940</mixed-citation><mixed-citation xml:lang="ru">Xu L., Zhang G., Zhao L., et al. Radiomics based on multiparametric magnetic resonance imaging to predict extraprostatic extension of prostate cancer // Front Oncol. 2020. Vol. 10. P. 940. doi: 10.3389/fonc.2020.00940</mixed-citation></citation-alternatives></ref><ref id="B30"><label>30.</label><citation-alternatives><mixed-citation xml:lang="en">Kuess P, Andrzejewski P, Nilsson D, et al. Association between pathology and texture features of multi parametric MRI of the prostate. Phys Med Biol. 2017;62(19):7833–7854. doi: 10.1088/1361-6560/aa884d</mixed-citation><mixed-citation xml:lang="ru">Kuess P., Andrzejewski P., Nilsson D., et al. Association between pathology and texture features of multi parametric MRI of the prostate // Phys Med Biol. 2017. Vol. 62, N 19. P. 7833–7854. doi: 10.1088/1361-6560/aa884d</mixed-citation></citation-alternatives></ref><ref id="B31"><label>31.</label><citation-alternatives><mixed-citation xml:lang="en">Riaz N, Afaq A, Akin O, et al. Pretreatment endorectal coil magnetic resonance imaging findings predict biochemical tumor control in prostate cancer patients treated with combination brachytherapy and external-beam radiotherapy. Int J Radiat Oncol Biol Phys. 2012;84(3):707–711. doi: 10.1016/j.ijrobp.2012.01.009</mixed-citation><mixed-citation xml:lang="ru">Riaz N., Afaq A., Akin O., et al. Pretreatment endorectal coil magnetic resonance imaging findings predict biochemical tumor control in prostate cancer patients treated with combination brachytherapy and external-beam radiotherapy // Int J Radiat Oncol Biol Phys. 2012. Vol. 84, N 3. P. 707–711. doi: 10.1016/j.ijrobp.2012.01.009</mixed-citation></citation-alternatives></ref><ref id="B32"><label>32.</label><citation-alternatives><mixed-citation xml:lang="en">Gnep K, Fargeas A, Gutiérrez-Carvajal RE, et al. Haralick textural features on T2-weighted MRI are associated with biochemical recurrence following radiotherapy for peripheral zone prostate cancer. J Magn Reson Imaging. 2017;45(1):103–117. doi: 10.1002/jmri.25335</mixed-citation><mixed-citation xml:lang="ru">Gnep K., Fargeas A., Gutiérrez-Carvajal R.E., et al. Haralick textural features on T2-weighted MRI are associated with biochemical recurrence following radiotherapy for peripheral zone prostate cancer // J Magn Reson Imaging. 2017. Vol. 45, N 1. P. 103–117. doi: 10.1002/jmri.25335</mixed-citation></citation-alternatives></ref><ref id="B33"><label>33.</label><citation-alternatives><mixed-citation xml:lang="en">Ginsburg SB, Rusu M, Kurhanewicz J, et al. Computer extracted texture features on T2w MRI to predict biochemical recurrence following radiation therapy for prostate cancer. SPIE. 2014;9035:903509. doi: 10.1117/12.2043937</mixed-citation><mixed-citation xml:lang="ru">Ginsburg S.B., Rusu M., Kurhanewicz J., et al. Computer extracted texture features on T2w MRI to predict biochemical recurrence following radiation therapy for prostate cancer // SPIE. 2014. Vol. 9035. P. 903509. doi: 10.1117/12.2043937</mixed-citation></citation-alternatives></ref><ref id="B34"><label>34.</label><citation-alternatives><mixed-citation xml:lang="en">Park SY, Kim CK, Park BK, et al. Prediction of biochemical recurrence following radical prostatectomy in men with prostate cancer by diffusion-weighted magnetic resonance imaging: Initial results. Eur Radiol. 2011;21(5):1111–1118. doi: 10.1007/s00330-010-1999-9</mixed-citation><mixed-citation xml:lang="ru">Park S.Y., Kim C.K., Park B.K., et al. Prediction of biochemical recurrence following radical prostatectomy in men with prostate cancer by diffusion-weighted magnetic resonance imaging: Initial results // European Radiology. 2011. Vol. 21, N 5. P. 1111–1118. doi: 10.1007/s00330-010-1999-9</mixed-citation></citation-alternatives></ref><ref id="B35"><label>35.</label><citation-alternatives><mixed-citation xml:lang="en">Woo S, Kim SY, Cho JY, et al. Preoperative evaluation of prostate cancer aggressiveness: Using ADC and ADC ratio in determining gleason score. AJR Am J Roentgenol. 2016;207(1):114–120. doi: 10.2214/AJR.15.15894</mixed-citation><mixed-citation xml:lang="ru">Woo S., Kim S.Y., Cho J.Y., et al. Preoperative evaluation of prostate cancer aggressiveness: Using ADC and ADC ratio in determining gleason score // AJR Am J Roentgenol. 2016. Vol. 207, N 1. P. 114–120. doi: 10.2214/AJR.15.15894</mixed-citation></citation-alternatives></ref><ref id="B36"><label>36.</label><citation-alternatives><mixed-citation xml:lang="en">Incoronato M, Aiello M, Infante T, et al. Radiogenomic analysis of oncological data: a technical survey. Int J Mol Sci. 2017;18(4):805. doi: 10.3390/ijms18040805</mixed-citation><mixed-citation xml:lang="ru">Incoronato M., Aiello M., Infante T., et al. Radiogenomic analysis of oncological data: a technical survey // Int J Mol Sci. 2017. Vol. 18, N 4. P. 805. doi: 10.3390/ijms18040805</mixed-citation></citation-alternatives></ref><ref id="B37"><label>37.</label><citation-alternatives><mixed-citation xml:lang="en">Jamshidi N, Margolis DJ, Raman S, et al. Multiregional radiogenomic assessment of prostate microenvironments with multiparametric MR imaging and DNA whole-exome sequencing of prostate glands with adenocarcinoma. Radiology. 2017;284(1):109–119. doi: 10.1148/radiol.2017162827</mixed-citation><mixed-citation xml:lang="ru">Jamshidi N., Margolis D.J., Raman S., et al. Multiregional radiogenomic assessment of prostate microenvironments with multiparametric MR imaging and DNA whole-exome sequencing of prostate glands with adenocarcinoma // Radiology. 2017. Vol. 284, N 1. P. 109–119. doi: 10.1148/radiol.2017162827</mixed-citation></citation-alternatives></ref><ref id="B38"><label>38.</label><citation-alternatives><mixed-citation xml:lang="en">Stoyanova R, Pollack A, Takhar M, et al. Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies. Oncotarget. 2016;7(33):53362–53376. doi: 10.18632/oncotarget.10523</mixed-citation><mixed-citation xml:lang="ru">Stoyanova R., Pollack A., Takhar M., et al. Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies // Oncotarget. 2016. Vol. 7, N 33. P. 53362–53376. doi: 10.18632/oncotarget.10523</mixed-citation></citation-alternatives></ref></ref-list></back></article>
