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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Digital Diagnostics</journal-id><journal-title-group><journal-title xml:lang="en">Digital Diagnostics</journal-title><trans-title-group xml:lang="ru"><trans-title>Digital Diagnostics</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Digital Diagnostics</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2712-8490</issn><issn publication-format="electronic">2712-8962</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">71633</article-id><article-id pub-id-type="doi">10.17816/DD71633</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>科学评论</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Emerging techniques in atherosclerosis imaging</article-title><trans-title-group xml:lang="ru"><trans-title>Новые методы визуализации атеросклероза</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>动脉粥样硬化成像的新方法</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0530-8306</contrib-id><name><surname>Syed</surname><given-names>Maaz B.J.</given-names></name><address><country country="GB">United Kingdom</country></address><email>maaz.syed@ed.ac.uk</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9984-8391</contrib-id><name><surname>Fletcher</surname><given-names>Alexander J.</given-names></name><address><country country="GB">United Kingdom</country></address><email>maaz.syed@ed.ac.uk</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3311-9599</contrib-id><name><surname>Forsythe</surname><given-names>Rachael O.</given-names></name><address><country country="GB">United Kingdom</country></address><email>maaz.syed@ed.ac.uk</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3005-6860</contrib-id><name><surname>Kaczynski</surname><given-names>Jakub</given-names></name><address><country country="GB">United Kingdom</country></address><email>maaz.syed@ed.ac.uk</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7971-4628</contrib-id><name><surname>Newby</surname><given-names>David E.</given-names></name><address><country country="GB">United Kingdom</country></address><email>maaz.syed@ed.ac.uk</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9847-5917</contrib-id><name><surname>Dweck</surname><given-names>Marc R.</given-names></name><address><country country="GB">United Kingdom</country></address><email>maaz.syed@ed.ac.uk</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2777-5071</contrib-id><name><surname>R. van Beek</surname><given-names>Edwin J.</given-names></name><address><country country="GB">United Kingdom</country></address><email>maaz.syed@ed.ac.uk</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>University of Edinburgh</institution></aff><pub-date date-type="preprint" iso-8601-date="2021-09-21" publication-format="electronic"><day>21</day><month>09</month><year>2021</year></pub-date><pub-date date-type="pub" iso-8601-date="2021-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2021</year></pub-date><volume>2</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>386</fpage><lpage>409</lpage><history><date date-type="received" iso-8601-date="2021-06-17"><day>17</day><month>06</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-06-17"><day>17</day><month>06</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Syed M.B., Fletcher A.J., Forsythe R.O., Kaczynski J., Newby D.E., Dweck M.R., R. van Beek E.J.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Syed M.B., Fletcher A.J., Forsythe R.O., Kaczynski J., Newby D.E., Dweck M.R., R. van Beek E.J.</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2021, Syed M., Fletcher A.J., Forsythe R.O., Kaczynski J., Newby D.E., Dweck M.R., R. van Beek E.J.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Syed M.B., Fletcher A.J., Forsythe R.O., Kaczynski J., Newby D.E., Dweck M.R., R. van Beek E.J.</copyright-holder><copyright-holder xml:lang="ru">Syed M.B., Fletcher A.J., Forsythe R.O., Kaczynski J., Newby D.E., Dweck M.R., R. van Beek E.J.</copyright-holder><copyright-holder xml:lang="zh">Syed M., Fletcher A.J., Forsythe R.O., Kaczynski J., Newby D.E., Dweck M.R., R. van Beek E.J.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://jdigitaldiagnostics.com/DD/article/view/71633">https://jdigitaldiagnostics.com/DD/article/view/71633</self-uri><abstract xml:lang="en"><p>Atherosclerosis is a chronic immunomodulated disease that affects multiple vascular beds and results in a significant worldwide disease burden. Conventional imaging modalities focus on the morphological features of atherosclerotic disease such as the degree of stenosis caused by a lesion. Modern CT, MR and positron emission tomography scanners have seen significant improvements in the rapidity of image acquisition and spatial resolution. This has increased the scope for the clinical application of these modalities. Multimodality imaging can improve cardiovascular risk prediction by informing on the constituency and metabolic processes within the vessel wall. Specific disease processes can be targeted using novel biological tracers and “smart” contrast agents. These approaches have the potential to inform clinicians of the metabolic state of atherosclerotic plaque.</p> <p>This review will provide an overview of current imaging techniques for the imaging of atherosclerosis and how various modalities can provide information that enhances the depiction of basic morphology.</p> <p>This publication is the reprint with Russian translation from original: Syed MB, Fletcher AJ, Forsythe RO, Kaczynski J, Newby DE, Dweck MR, van Beek EJ. Emerging techniques in atherosclerosis imaging. <italic>Br J Radiol.</italic> 2019;92(1103):20180309. doi: 10.1259/bjr.20180309.</p></abstract><trans-abstract xml:lang="ru"><p>Атеросклероз ― это хроническое иммуномодулируемое заболевание, которое поражает артерии и приводит к значительному бремени болезней во всём мире. Традиционные методы визуализации сосредоточены на морфологических особенностях атеросклероза, таких как степень стеноза, вызванного поражением сосудов. С появлением современных компьютерных, магнитно-резонансных и позитронно-эмиссионных томографов повысились скорость получения изображений и пространственное разрешение, что обеспечивает широкие возможности их применения в клинической практике. Комплексная визуализация способствует более точному прогнозированию сердечно- сосудистого риска и даёт развёрнутую информацию о состоянии и метаболических процессах в стенках сосудов. Конкретные этапы развития болезни можно выявить с помощью биологических индикаторов и «умных» контрастных веществ. Эти подходы позволяют врачам оценить метаболическое состояние атеросклеротической бляшки.</p> <p>В обзоре представлены данные о современных методах визуализации атеросклероза, применение которых поможет выявить основные морфологические характеристики заболевания.</p> <p>Данная публикация является перепечатанной версией статьи с переводом оригинала [Syed MB, Fletcher AJ, Forsythe RO, Kaczynski J, Newby DE, Dweck MR, van Beek EJ. Emerging techniques in atherosclerosis imaging. <italic>Br J Radiol.</italic> 2019;92(1103):20180309. doi: 10.1259/bjr.20180309] на русский язык.</p></trans-abstract><trans-abstract xml:lang="zh"><p>动脉粥样硬化是一种慢性免疫调节疾病，影响动脉，在全世界造成相当大的疾病负担。传统的影像学方法侧重于动脉粥样硬化的形态特征，如血管病变引起的狭窄程度。随着现代计算机、磁共振和正电子发射断层扫描的出现，图像获取率和空间分辨率都有所提高，为其在临床中的应用提供了广泛的可能性。集成成像有助于更准确地预测心血管风险，并提供有关血管壁状态和代谢过程的详细信息。 可以使用生物指标和“智能”造影剂识别疾病发展的特定阶段。 这些方法使医生能够评估动脉粥样硬化斑块的代谢状态。</p> <p>综述介绍了现代动脉粥样硬化影像学方法的数据，应用这些方法将有助于揭示疾病的主要形态特征。</p> <p>本出版物是该文章的重印版，并附有原文的翻译[Syed MB, Fletcher AJ, Forsythe RO, Kaczynski J, Newby DE, Dweck MR, van Beek EJ.Emerging techniques in atherosclerosis imaging.Br J Radiol 2019;92(1103):20180309. doi: 10.1259/bjr.20180309]成俄语。</p></trans-abstract><kwd-group xml:lang="en"><kwd>atherosclerosis</kwd><kwd>ultrasound diagnostics</kwd><kwd>radiology</kwd><kwd>magnetic resonance imaging</kwd><kwd>positron emission tomography</kwd><kwd>cardiovascular risk</kwd><kwd>optical coherence tomography</kwd><kwd>molecular imaging</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>атеросклероз</kwd><kwd>ультразвуковое исследование</kwd><kwd>лучевая диагностика</kwd><kwd>магнитно-резонансная томография</kwd><kwd>позитронно-эмиссионная томография</kwd><kwd>сердечно-сосудистый риск</kwd><kwd>оптическая когерентная томография</kwd><kwd>молекулярная визуализация</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>动脉粥样硬化</kwd><kwd>超声程序</kwd><kwd>放射诊断</kwd><kwd>磁共振成像</kwd><kwd>正电子发射断层扫描</kwd><kwd>心血管风险</kwd><kwd>光学相干断层扫描</kwd><kwd>分子成像</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Herrington W, Lacey B, Sherliker P, et al. 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