Mitral valve calcinosis as an important finding during heart examination
- Authors: Filatova D.A.1, Mershina E.A.1, Plotnikova M.L.1, Lisitskaya M.V.1, Sinitsyn V.E.1
-
Affiliations:
- Medical Research and Educational Center of Lomonosov Moscow State University
- Section: Original Study Articles
- Submitted: 17.12.2023
- Accepted: 24.01.2024
- Published: 19.06.2024
- URL: https://jdigitaldiagnostics.com/DD/article/view/624754
- DOI: https://doi.org/10.17816/DD624754
- ID: 624754
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Abstract
Background: Mitral valve calcinosis (MVC) is a chronic degenerative process in the fibrous structures of the mitral valve (MV), at advanced stages increasing the risk of endocarditis, cardiac rhythm disturbances and contributing to the pattern of cardiovascular mortality. The etiology of MVC is still a controversial issue, but the contribution of atherosclerosis to its development is currently undisputed. The prevalence of MVC varies in different age groups and on average is higher in people with cardiovascular disease.
Aim: To assess the prevalence of MVC in patients undergoing computed tomographic (CT) angiography; to identify the relationship between aortic and mitral valve calcinosis and coronary calcium index and signs of remodeling.
Materials and methods: A retrospective study of 336 patients who underwent CT coronary angiography with intravenous contrast enhancement at the Lomonosov Moscow State University Hospital between 13.11.2020 and 14.05.2022 was conducted.
Results: The study showed a high prevalence of aortic and mitral valve calcinosis in the population of people undergoing cardiovascular examination, as well as the presence of a relationship between valve calcinosis and coronary calcium index.
Conclusions: Detection of MVC in patients during routine examination plays an important role in predicting further treatment and outcome, because valve calcinosis is an indirect indicator of coronary heart disease risk. Although valve calcinosis is usually an incidental finding on examination, it may indicate a high cardiovascular risk and should be a reason for further evaluation if clinically necessary.
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Дополнительная информация
Конфликт интересов.
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Участие авторов.
Филатова Д.А. – формирование группы исследования, проведение статистического анализа данных, написание текста статьи. Мершина Е.А. – разработка концепции исследования, редактирование текста статьи. Плотникова М.Л. – редактирование текста статьи. Лисицкая М.В. – разработка концепции исследования, редактирование текста статьи. Синицын В.Е. – разработка концепции исследования, утверждение окончательного варианта текста. Все авторы внесли значимый вклад в проведение исследования и подготовку статьи, прочли и одобрили финальную версию статьи перед публикацией.
About the authors
Daria A. Filatova
Medical Research and Educational Center of Lomonosov Moscow State University
Author for correspondence.
Email: dariafilatova.msu@mail.ru
ORCID iD: 0000-0002-0894-1994
SPIN-code: 2665-5973
Postgraduate Student of Radiology Department of Lomonosov Moscow State University, radiologist of Radiology Department of Lomonosov Moscow State University Medical Research and Education Center
Russian Federation, Moscow, Lomonosovskiy av., 27/10Elena A. Mershina
Medical Research and Educational Center of Lomonosov Moscow State University
Email: elena_mershina@mail.ru
ORCID iD: 0000-0002-1266-4926
SPIN-code: 6897-9641
PhD in Medical Sciences, head of the Department of X-ray diagnostics, leading researcher at the Department of radiation diagnostics of the Medical scientific and educational center
Russian Federation, Moscow, Lomonosovskiy av., 27/10Maria L. Plotnikova
Medical Research and Educational Center of Lomonosov Moscow State University
Email: maria_plotnikova@inbox.ru
ORCID iD: 0000-0001-7533-9867
radiologist of the Radiology Department of Medical Research and Educational Center of Lomonosov Moscow State University
Russian Federation, Moscow, Lomonosovskiy av., 27/10Mariya V. Lisitskaya
Medical Research and Educational Center of Lomonosov Moscow State University
Email: lissenok@inbox.ru
ORCID iD: 0000-0002-8402-7643
PhD, research fellow of the Radiology Department of Medical Research and Educational Center of Lomonosov Moscow State University
Russian Federation, Moscow, Lomonosovskiy av., 27/10Valentin E. Sinitsyn
Medical Research and Educational Center of Lomonosov Moscow State University
Email: vsin@mail.ru
ORCID iD: 0000-0002-5649-2193
SPIN-code: 8449-6590
Professor, Doc. of Med. Sc., Head of Radiology department of Medical Research and Educational Center, Radiology Chair in Lomonosov Moscow State University
Russian Federation, Moscow, Lomonosovskiy av., 27/10References
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